Therapeutic Potentials of Adansonia digitata (Bombacaceae) Stem Bark in Plasmodium berghei-Infected Mice
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چکیده
منابع مشابه
Antimalarial and Reno-protective Potentials of Combined Stem Bark Extracts of Khaya grandifoliola and Enantia chlorantha in Plasmodium Infected Mice
Background: Malaria is a worldwide threat, which affects millions of people. Although several antimalarial has been reported, they are either not effective or toxic. This study evaluated the antimalarial efficacy and safety of stem bark aqueous extracts of Khaya grandifoliola (KG) and Enantia chlorantha (EC) in Plasmodium berghie (NK65S) infected Swiss mice. Methods: Forty-two animals were gro...
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Background: Newbouldia laevis and Crateva adansonii are popular plants used traditionally in the management of patients with malaria infection in Nigeria. In this study, the acute toxicity and anti-plasmodial effects of the leaf extracts of Newbouldia laevis and Crateva adansonii were investigated in mice. Methods: The Anti-plasmodial activities of both extracts were investigated individual...
متن کاملAntioxidant activity of the methanol stem bark extract of Uapaca togoensis (pax) in mice exposed to Plasmodium berghei NK65
Background & Aim: Oxidative stress has been linked to the development of systemic complications in malaria infection. Recent approaches in treatment of malaria suggest that the control of oxidative stress in infected patients may be of therapeutic advantage. The stem bark and leaves of Uapaca togoensis are used locally in the treatment of various disease...
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Background: Anti-plasmodial activities of the methanol stem bark extracts of Nauclea latifolia, and Terminalia glaucescens were investigated in mice infected with Plasmodium berghei. Methods: A total of 24 Plasmodium berghei infected (P. berghei infected) mice were divided into 8 groups of 3 each. Groups A-F were given 100, 300 or 500 mg/kg of either extracts. Groups G and H received 2 mL norm...
متن کاملEthanol Extract of Blighia sapida Stem Bark Show Remarkable Prophylactic Activity in Experimental Plasmodium berghei–Infected Mice
This work explores the antiplasmodial potential of ethanol extract of Blighia sapida (Lin. Sapindaceae) in chloroquine (CQ)-resistant Plasmodium berghei (ANKA strain)-infected mice. Chloroquine-resistant (ANKA) strain of P berghei was inoculated intraperitoneally into Swiss albino mice. Mice were treated orally for 4 consecutive days, before and after inoculation (prophylactic, suppressive, and...
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ژورنال
عنوان ژورنال: Journal of Biological Sciences
سال: 2015
ISSN: 1727-3048
DOI: 10.3923/jbs.2015.78.84